ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemexV

efflux pump component

Nucleotide ChangeT-82C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime|ceftazidime avibactam|cefepime|ceftolozane tazobactam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors.

PMID 36399436 · 2022

The mutation increases resistance to cephalosporins and cephalosporin/beta-lactamase inhibitor combinations.

Mutation Information

mexV: c.T-82C

Nucleotide Change: T-82C
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime|ceftazidime avibactam|cefepime|ceftolozane tazobactam
Validation Method: susceptibility testing in engineered mutants
Source Database: Reslit

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