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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations mutYC-142T

GenemutY

DNA glycosylase

Nucleotide ChangeC-142T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: trimethoprim
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Evolution of Antimicrobial Resistance through Adaptive Laboratory Evolution

PMID 36625217 · 2023

MutY promoter mutation increases mutation rate, contributing to trimethoprim resistance.

Mutation Information

Nucleotide Change: C-142T
Organisms: Escherichia coli
Confers Resistance To: trimethoprim
Validation Method: genomic resequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research