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Browse Mutations pbp2D365A

Genepbp2

penicillin-binding protein 2

Protein ChangeD365A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: carbapenems|cephalosporins
Organisms: Acinetobacter baumannii
Papers: 1

Paper Information1

1

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.

PMID 36787358 · 2023

Mutations in the zinc-binding site of PBP2 lead to reduced susceptibility to carbapenems and cephalosporins.

Mutation Information

Protein Change: D365A
Organisms: Acinetobacter baumannii
Confers Resistance To: carbapenems|cephalosporins
Validation Method: antibiotic resistance assays
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research