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Browse Mutations mphIT166E

GenemphI

macrolide kinase

Protein ChangeT166E

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: azithromycin|telithromycin
Organisms: E. coli, Bacillus subtilis
Papers: 1

Paper Information1

1

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.

PMID 29317655 · 2018

Mutations at position 40 and 211 are required for resistance to C3 cladinose macrolides

Mutation Information

Protein Change: T166E
Organisms: E. coli, Bacillus subtilis
Confers Resistance To: azithromycin|telithromycin
Validation Method: mutagenesis and antibiotic susceptibility testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research