Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Performance of a broth microdilution assay for routine minimum inhibitory concentration determination of 14 anti-tuberculous drugs against the Mycobacterium tuberculosis complex based on the EUCAST reference protocol.
Mutations in atpE are associated with bedaquiline resistance.
High Prevalence of atpE Mutations in Bedaquiline-Resistant Mycobacterium tuberculosis Isolates, Russia.
mutations in atpE are associated with bedaquiline resistance
Whole genome sequencing-based detection of extensively drug-resistant tuberculosis from Ethiopia.
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
All mutations were confirmed by DNA sequencing.
In Vitro Study of Stepwise Acquisition of rv0678 and atpE Mutations Conferring Bedaquiline Resistance.
Empirical ways to identify novel Bedaquiline resistance mutations in AtpE.
These mutations were identified as resistance-associated variants through structural and functional analysis.
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Variants in atpE are associated with bedaquiline resistance.
Bedaquiline for treatment of non-tuberculous mycobacteria (NTM): a systematic review and meta-analysis.
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
At least 4-fold increase in bedaquiline MIC
Mycobacterium tuberculosis atpE with mutation conferring resistance to bedaquiline; CARD accession: CARD:3007854
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