ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemurA

antibiotic-resistant murA transferase

Protein ChangeT396N

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogReslit

Overview

Mechanism: single resistance variant, UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA
Resistance To: fosfomycin
Organisms: Staphylococcus aureus
Papers: 2

Paper Information2

Whole-Genome Sequencing-Based Screening of MRSA in Patients and Healthcare Workers in Public Hospitals in Benin.

PMID 37630513 · 2023

Mutation Information

murA: p.T396N

Protein Change: T396N
Organisms: Staphylococcus aureus
Confers Resistance To: fosfomycin
Source Database: Reslit

Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples.

PMID 26793179 · 2015

Staphylococcus aureus murA with mutation conferring resistance to fosfomycin; CARD accession: CARD:3003776

Mutation Information

murA: p.T396N

Protein Change: T396N
Organisms: Staphylococcus aureus
Confers Resistance To: fosfomycin
Effect on Function: single resistance variant
Source Database: Card Database

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