ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneadeS

sensor kinase

Protein ChangeD167N

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: tigecycline, carbapenems
Organisms: Acinetobacter baumannii
Papers: 2

Paper Information2

Transcriptome Remodeling of Acinetobacter baumannii during Infection and Treatment.

PMID 28270585 · 2017

Mutation Information

adeS: p.D167N

Protein Change: D167N
Organisms: Acinetobacter baumannii
Confers Resistance To: tigecycline
Validation Method: transcriptome analysis
Source Database: Reslit

Global genomic epidemiology of chromosomally mediated non-enzymatic carbapenem resistance in Acinetobacter baumannii: on the way to predict and modify resistance.

PMID 37869654 · 2023

Mutation in AdeS is associated with increased carbapenem resistance.

Mutation Information

adeS: p.D167N

Protein Change: D167N
Confers Resistance To: carbapenems
Validation Method: correlation with carbapenem MICs and computational predictions; Structural and functional analysis
Source Database: Reslit

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