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Browse Mutations emrRW140R

GeneemrR

efflux pump

Protein ChangeW140R

Nucleotide ChangeT418A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delafloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.

PMID 37882542 · 2023

Mutations in emrR were primarily observed in DLX-challenged clones.

Mutation Information

emrR: p.W140R / c.T418A

Protein Change: W140R
Nucleotide Change: T418A
Organisms: Escherichia coli
Confers Resistance To: delafloxacin
Validation Method: complementation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research