ResLit - Antimicrobial Resistance Gene & Mutation Database

Nucleotide ChangeG57T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increase of the beta-lactamase expression
Resistance To: ampicillin
Organisms: Campylobacter coli, Campylobacter jejuni
Papers: 1

Paper Information1

Combined genomic-proteomic approach in the identification of Campylobacter coli amoxicillin-clavulanic acid resistance mechanism in clinical isolates.

PMID 38029165 · 2023

The G57T mutation in the blaOXA61 promoter region was associated with increased beta-lactamase expression and ampicillin resistance.

Mutation Information

blaOXA61: c.G57T

Nucleotide Change: G57T
Organisms: Campylobacter coli, Campylobacter jejuni
Confers Resistance To: ampicillin
Effect on Function: increase of the beta-lactamase expression
Validation Method: genomic analysis and mass spectrometry
Source Database: Reslit

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