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Browse Mutations ptsIV488F

GeneptsI

Enzyme IIAGlc

Protein ChangeV488F

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: meropenem|ceftriaxone|ertapenem|amikacin|polymyxin b
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility.

PMID 38190524 · 2024

Mutation Information

Protein Change: V488F
Organisms: Escherichia coli
Confers Resistance To: meropenem|ceftriaxone|ertapenem|amikacin|polymyxin b
Validation Method: Growth curve analysis, complementation with wild-type ptsI, time-kill assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research