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Browse Mutations nfxBGC115TA

GenenfxB

efflux pump regulator

Nucleotide ChangeGC115TA

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss-of-function
Resistance To: ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

nfxB as a novel target for analysis of mutation spectra in Pseudomonas aeruginosa.

PMID 23762483 · 2013

Inactivating mutations in nfxB lead to resistance to ciprofloxacin

Mutation Information

nfxB: c.GC115TA

Nucleotide Change: GC115TA
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin
Effect on Function: loss-of-function
Validation Method: sequencing analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research