ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2x

penicillin-binding protein 2X

Protein ChangeG398A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: penicillin
Organisms: Streptococcus agalactiae
Papers: 2

Paper Information2

First Case in Korea of Group B Streptococcus With Reduced Penicillin Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Protein 2X.

PMID 30809991 · 2019

Amino acid substitutions in PBP2X are associated with reduced penicillin susceptibility.

Mutation Information

pbp2x: p.G398A

Protein Change: G398A
Organisms: Streptococcus agalactiae
Confers Resistance To: penicillin
Validation Method: sequencing
Source Database: Reslit

Invasive bacterial disease trends and characterization of group B streptococcal isolates among young infants in southern Mozambique, 2001-2015.

PMID 29351318 · 2018

mutations in pbp2x confer reduced penicillin susceptibility

Mutation Information

pbp2x: p.G398A

Protein Change: G398A
Organisms: Streptococcus agalactiae
Confers Resistance To: penicillin
Validation Method: whole genome sequencing and antimicrobial susceptibility testing
Source Database: Reslit

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