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Browse Mutations ompK35121insG

outer membrane porin

Nucleotide Change121insG

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: non-functional
Resistance To: carbapenems
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

1

Molecular analysis of clinical isolates of ceftazidime-avibactam-resistant Klebsiella pneumoniae

PMID 33775814 · 2021

disruption of ompK35 leads to reduced susceptibility to carbapenems

Mutation Information

ompK35: c.121insG

Nucleotide Change: 121insG
Organisms: Klebsiella pneumoniae
Confers Resistance To: carbapenems
Effect on Function: non-functional
Validation Method: gene disruption analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research