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Browse Mutations dsbAL456P

GenedsbA

thiol:disulfide oxidoreductase chaperone

Protein ChangeL456P

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin
Papers: 1

Paper Information1

1

Emergence of Resistant Escherichia coli Mutants in Microfluidic On-Chip Antibiotic Gradients.

PMID 35391738 · 2022

Mutations in dsbA, affecting disulfide bond formation and contributing to ciprofloxacin resistance.

Mutation Information

Protein Change: L456P
Confers Resistance To: ciprofloxacin
Validation Method: whole-genome sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research