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Browse Mutations pbp3L169P

Genepbp3

penicillin-binding protein

Protein ChangeL169P

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: significant increase in the MIC value for CAZ/AVI
Resistance To: ceftazidime|avibactam
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Molecular mechanisms underlying bacterial resistance to ceftazidime/avibactam.

PMID 35891616 · 2022

Mutation Information

Protein Change: L169P
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa
Confers Resistance To: ceftazidime|avibactam
Effect on Function: significant increase in the MIC value for CAZ/AVI
Validation Method: reported in cited literature
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research