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Browse Mutations rpoCG498D

GenerpoC

Protein ChangeG498D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: oxacillin|cefoxitin|imipenem
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Metabolic remodeling by RNA polymerase gene mutations is associated with reduced β-lactam susceptibility in oxacillin-susceptible MRSA.

PMID 38988221 · 2024

Mutation Information

Protein Change: G498D
Organisms: Staphylococcus aureus
Confers Resistance To: oxacillin|cefoxitin|imipenem
Validation Method: MIC testing; metabolomics analysis and antibiotic susceptibility testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research