ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeK28E

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: 30S ribosomal protein S5
Resistance To: spectinomycin
Organisms: Neisseria gonorrhoeae, Neisseria meningitidis
Papers: 1

Paper Information1

Neisseria gonorrhoeae strain with high-level resistance to spectinomycin due to a novel resistance mechanism (mutated ribosomal protein S5) verified in Norway.

PMID 23183436 · 2013

Mutation seen together with V27 deletion

rpsE

Mutation Information

rpsE: p.K28E

Protein Change: K28E
Organisms: Neisseria gonorrhoeae, Neisseria meningitidis
Confers Resistance To: spectinomycin
Effect on Function: 30S ribosomal protein S5
Source Database: ResFinder DatabaseReference Gene Catalog

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