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Browse Mutations dfrBN60I

GenedfrB

dihydrofolate reductase

Protein ChangeN60I

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: Target modification, dihydrofolate reductase DfrB
Resistance To: trimethoprim
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance.

PMID 9054967 · 1997

Mutation Information

Protein Change: N60I
Organisms: Staphylococcus aureus
Confers Resistance To: trimethoprim
Effect on Function: Target modification
Source Database: ResFinder Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research