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Browse Mutations rpoCD244Y

GenerpoC

Protein ChangeD244Y

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: vancomycin
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

1

In vitro selection, via serial passage, of Clostridium difficile mutants with reduced susceptibility to fidaxomicin or vancomycin.

PMID 23887866 · 2014

Clostridioides difficile rpoC with mutation conferring resistance to vancomycin; CARD accession: CARD:3004681

Mutation Information

Protein Change: D244Y
Organisms: Clostridioides difficile
Confers Resistance To: vancomycin
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research