ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeA12S

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, regulatory protein SoxS
Resistance To: multiple antibiotics, ampicillin|phenicols|quinolones|rifampicin|tetracycline
Organisms: Escherichia coli
Papers: 1

Paper Information1

A novel alanine to serine substitution mutation in SoxS induces overexpression of efflux pumps and contributes to multidrug resistance in clinical Escherichia coli isolates.

PMID 25921515 · 2015

Escherichia coli soxS with mutation conferring antibiotic resistance; CARD accession: CARD:3003511

Mutation Information

soxS: p.A12S

Protein Change: A12S
Organisms: Escherichia coli
Confers Resistance To: multiple antibiotics
Effect on Function: single resistance variant
Source Database: Card Database

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