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Browse Mutations rdxAG112fs

GenerdxA

oxygen-insensitive NADPH nitroreductase

Protein ChangeG112fs

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: frameshift mutation
Resistance To: metronidazole
Organisms: Helicobacter pylori
Papers: 1

Paper Information1

1

Genetic Determinants and Prediction of Antibiotic Resistance Phenotypes in Helicobacter pylori.

PMID 30621024 · 2019

Helicobacter pylori rdxA mutation conferring resistance to metronidazole; CARD accession: CARD:3007055

Mutation Information

Protein Change: G112fs
Organisms: Helicobacter pylori
Confers Resistance To: metronidazole
Effect on Function: frameshift mutation
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research