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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations pbp2L421P

Genepbp2

penicillin-binding protein 2

Protein ChangeL421P

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftriaxone
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

Multidrug-resistant Neisseria gonorrhoeae infection in heterosexual men with reduced susceptibility to ceftriaxone, first report in Thailand.

PMID 34737332 · 2021

Mutation in PBP2 associated with reduced ceftriaxone susceptibility

Mutation Information

Protein Change: L421P
Organisms: Neisseria gonorrhoeae
Confers Resistance To: ceftriaxone
Validation Method: molecular docking and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research