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Browse Mutations Rv0678Y145Ter

protein

Protein ChangeY145Ter

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: nonsense mutation
Resistance To: bedaquiline, clofazimine
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

PMID 978-92-4-008241-0

Mycobacterium tuberculosis Rv0678 with mutation conferring resistance to bedaquiline; CARD accession: CARD:3007674

Mycobacterium tuberculosis Rv0678 with mutation conferring resistance to clofazimine; CARD accession: CARD:3007852

Mutation Information

Rv0678: p.Y145Ter

Protein Change: Y145Ter
Organisms: Mycobacterium tuberculosis
Confers Resistance To: bedaquilineclofazimine
Effect on Function: nonsense mutation
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research