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Browse Mutations sigIK270Q

GenesigI

Protein ChangeK270Q

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

PMID 30337678 · 2018

Mycobacterium tuberculosis sigI mutations conferring resistance to isoniazid; CARD accession: CARD:3004932

Mutation Information

Protein Change: K270Q
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research