ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2

penicillin-binding protein 2

Protein ChangeG482S

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: beta lactams
Organisms: Neisseria meningitidis
Papers: 1

Paper Information1

Crystal structures of penicillin-binding protein 2 from penicillin-susceptible and -resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistance.

PMID 18986991 · 2009

Neisseria meningititis PBP2 conferring resistance to beta-lactam; CARD accession: CARD:3003937

Mutation Information

pbp2: p.G482S

Protein Change: G482S
Organisms: Neisseria meningitidis
Confers Resistance To: beta lactams
Effect on Function: single resistance variant
Source Database: Card Database

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