ResLit - Antimicrobial Resistance Gene & Mutation Database

phosphatidate cytidylyltransferase

Protein ChangeD222N

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, phosphatidate cytidylyltransferase CdsA
Resistance To: daptomycin
Organisms: Streptococcus oralis
Papers: 1

Paper Information1

Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis/oralis by a Novel Mechanism.

Streptococcus mitis CdsA with mutation conferring daptomycin resistance; CARD accession: CARD:3004097

cdsA

Protein Change: D222N
Organisms: Streptococcus oralis
Confers Resistance To: daptomycin
Effect on Function: single resistance variant; phosphatidate cytidylyltransferase CdsA
Source Database: Card DatabaseReference Gene Catalog

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