ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD237Y

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoC
Resistance To: fidaxomicin
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

Antibacterials Developed to Target a Single Organism: Mechanisms and Frequencies of Reduced Susceptibility to the Novel Anti-Clostridium difficile Compounds Fidaxomicin and LFF571.

PMID 26834162 · 2016

rpoC

Mutation Information

rpoC: p.D237Y

Protein Change: D237Y
Organisms: Clostridioides difficile
Confers Resistance To: fidaxomicin
Effect on Function: DNA-directed RNA polymerase subunit beta RpoC
Source Database: Reference Gene Catalog

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