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Browse Mutations rpsJRATHK53Q

GenerpsJ

Protein ChangeRATHK53Q

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: 30S ribosomal protein S10
Resistance To: tigecycline
Organisms: Enterococcus faecalis, Enterococcus faecium
Papers: 3

Paper Information3

1

Rampant Parasexuality Evolves in a Hospital Pathogen during Antibiotic Selection.

PMID 26060280 · 2015

rpsJ

Mutation Information

rpsJ: p.RATHK53Q

Protein Change: RATHK53Q
Organisms: Enterococcus faecalis
Confers Resistance To: tigecycline
Effect on Function: 30S ribosomal protein S10
Source Database: Reference Gene Catalog

2

Focal epithelial hyperplasia (Heck's disease) in a Sudanese girl: case report.

PMID 2612415 · 1989

rpsJ

Mutation Information

rpsJ: p.RATHK53Q

Protein Change: RATHK53Q
Organisms: Enterococcus faecalis
Confers Resistance To: tigecycline
Effect on Function: 30S ribosomal protein S10
Source Database: Reference Gene Catalog

3

The ribosomal S10 protein is a general target for decreased tigecycline susceptibility.

PMID 26124155 · 2015

rpsJ

Mutation Information

rpsJ: p.RATHK53Q

Protein Change: RATHK53Q
Organisms: Enterococcus faecium
Confers Resistance To: tigecycline
Effect on Function: 30S ribosomal protein S10
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research