ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneliaS

two-component system histidine kinase

Protein ChangeG92D

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: sensor histidine kinase LiaS
Resistance To: daptomycin
Organisms: Enterococcus faecium
Papers: 1

Paper Information1

Sequential steps of daptomycin resistance in Enterococcus faecium and reversion to hypersusceptibility through IS-mediated inactivation of the liaFSR operon.

PMID 27353469 · 2016

liaS

Mutation Information

liaS: p.G92D

Protein Change: G92D
Organisms: Enterococcus faecium
Confers Resistance To: daptomycin
Effect on Function: sensor histidine kinase LiaS
Source Database: Reference Gene Catalog

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