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Browse Mutations pbp1aP623L

penicillin-binding protein 1A

Protein ChangeP623L

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: penicillin-binding protein PBP-1A
Resistance To: beta lactams
Organisms: Helicobacter pylori
Papers: 1

Paper Information1

1

Multiple amino acid substitutions in penicillin-binding protein-1A confer amoxicillin resistance in refractory Helicobacter pylori infection.

PMID 35995672 · 2023

pbp1a

Mutation Information

Protein Change: P623L
Organisms: Helicobacter pylori
Confers Resistance To: beta lactams
Effect on Function: penicillin-binding protein PBP-1A
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research