ResLit - Antimicrobial Resistance Gene & Mutation Database

GenenalC

DNA gyrase inhibitor

Protein ChangeS127P

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: efflux system transcriptional repressor NalC
Resistance To: carbapenems
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

MexAB-OprM hyperexpression in NalC-type multidrug-resistant Pseudomonas aeruginosa: identification and characterization of the nalC gene encoding a repressor of PA3720-PA3719.

PMID 15387820 · 2004

nalC

Mutation Information

nalC: p.S127P

Protein Change: S127P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbapenems
Effect on Function: efflux system transcriptional repressor NalC
Source Database: Reference Gene Catalog

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