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Browse Mutations dfrBL25I

GenedfrB

dihydrofolate reductase

Protein ChangeL25I

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: dihydrofolate reductase DfrB
Resistance To: trimethoprim
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Resistance to antibacterial antifolates in multidrug-resistant Staphylococcus aureus: prevalence estimates and genetic basis.

PMID 36935372 · 2023

dfrB

Mutation Information

Protein Change: L25I
Organisms: Staphylococcus aureus
Confers Resistance To: trimethoprim
Effect on Function: dihydrofolate reductase DfrB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research