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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations mprFL431F

GenemprF

a gene which contributes to membrane charge through lysinylation of PG

Protein ChangeL431F

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF
Resistance To: daptomycin|vancomycin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Effect of a Point Mutation in mprF on Susceptibility to Daptomycin, Vancomycin, and Oxacillin in an MRSA Clinical Strain.

PMID 29887848 · 2018

mprF

Mutation Information

Protein Change: L431F
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin|vancomycin
Effect on Function: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research