ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemprF

a gene which contributes to membrane charge through lysinylation of PG

Protein ChangeS829L

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF
Resistance To: daptomycin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Daptomycin Resistant Staphylococcus aureus Clinical Strain With Novel Non-synonymous Mutations in the mprF and vraS Genes: A New Insight Into Daptomycin Resistance.

PMID 30459746 · 2018

mprF

Mutation Information

mprF: p.S829L

Protein Change: S829L
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin
Effect on Function: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF
Source Database: Reference Gene Catalog

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