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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations ampRE274fs

GeneampR

LysR-type transcriptional regulator

Protein ChangeE274fs

Nucleotide ChangeGAG->TGA

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime
Papers: 1

Paper Information1

1

Rapid Decline of Ceftazidime Resistance in Antibiotic-Free and Sublethal Environments Is Contingent on Genetic Background.

PMID 35291010 · 2022

original mutation in ParR-CAZ

Mutation Information

ampR: p.E274fs / c.GAG->TGA

Protein Change: E274fs
Nucleotide Change: GAG->TGA
Confers Resistance To: ceftazidime
Validation Method: whole-genome sequencing and β-lactamase activity measurements
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research