ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeT428P

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: inactivation, D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB
Resistance To: ceftazidime, cephalosporins
Organisms: Pseudomonas aeruginosa
Papers: 3

Paper Information3

Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein.

Inactivation of dacB leads to high-level β-lactam resistance.

Deciphering β-lactamase-independent β-lactam resistance evolution trajectories in Pseudomonas aeruginosa.

dacB

Protein Change: T428P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: cephalosporins
Effect on Function: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB
Source Database: Reference Gene Catalog

Single-layer end-on continuous suture of colonic anastomoses.

dacB

Protein Change: T428P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: cephalosporins
Effect on Function: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB
Source Database: Reference Gene Catalog

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