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Browse Mutations fimHH166Y

GenefimH

type 1 fimbriae tip adhesin

Protein ChangeH166Y

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased adhesion and urovirulence
Resistance To: fluoroquinolones
Papers: 1

Paper Information1

1

Role of homologous recombination in adaptive diversification of extraintestinal Escherichia coli.

PMID 23123908 · 2013

The H166Y mutation in FimH is associated with increased adhesion and urovirulence in E. coli.

Mutation Information

Protein Change: H166Y
Confers Resistance To: fluoroquinolones
Effect on Function: increased adhesion and urovirulence
Validation Method: mutant analysis in uropathogenic E. coli strains
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research