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Browse Mutations phoQR423C

GenephoQ

Protein ChangeR423C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: colistin
Organisms: Enterobacter cloacae
Papers: 1

Paper Information1

1

Clinical characteristics, molecular epidemiology and mechanisms of colistin heteroresistance in Enterobacter cloacae complex.

PMID 40115074 · 2025

Mutations in phoQ contribute to colistin heteroresistance.

Mutation Information

Protein Change: R423C
Organisms: Enterobacter cloacae
Confers Resistance To: colistin
Validation Method: non-synonymous substitutions in phoQ among colistin-heteroresistant isolates: R423C (n = 5)
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research