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Browse Mutations folM67fs

GenefolM

Dihydrofolate reductase

Protein Change67fs

Nucleotide Change67del

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: early termination of the protein following residue 92
Resistance To: sulfamethoxazole
Organisms: Burkholderia pseudomallei
Papers: 1

Paper Information1

1

Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm.

PMID 28874476 · 2017

Mutations in folM lead to reduced folM function and contribute to sulfamethoxazole resistance.

Mutation Information

folM: p.67fs / c.67del

Protein Change: 67fs
Nucleotide Change: 67del
Organisms: Burkholderia pseudomallei
Confers Resistance To: sulfamethoxazole
Effect on Function: early termination of the protein following residue 92
Validation Method: MIC testing and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research