ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefbiC

non-essential gene involved in activation of delamanid and pretomanid

Protein ChangeT89S

Nucleotide ChangeA266C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delamanid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Investigation of delamanid, bedaquiline, and linezolid resistance rates and related gene mutations in multidrug-resistant Mycobacterium tuberculosis in regional tuberculosis reference laboratories of Iran.

PMID 40817101 · 2025

Mutation Information

fbiC: p.T89S / c.A266C

Protein Change: T89S
Nucleotide Change: A266C
Organisms: Mycobacterium tuberculosis
Confers Resistance To: delamanid
Validation Method: sequencing
Source Database: Reslit

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