ResLit - Antimicrobial Resistance Gene & Mutation Database

GenenfsA

nitroreductase

Protein ChangeR169C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: nitrofurans, nitrofurantoin
Organisms: Vibrio cholerae
Papers: 2

Paper Information2

Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing to enhance genomic surveillance.

PMID 41369527 · 2025

Mutation Information

nfsA: p.R169C

Protein Change: R169C
Confers Resistance To: nitrofurans
Validation Method: detected in 100% of ST69 O1 isolates
Source Database: Reslit

Outbreak of Imported Seventh Pandemic Vibrio cholerae O1 El Tor, Algeria, 2018.

PMID 35608654 · 2022

Mutation Information

nfsA: p.R169C

Protein Change: R169C
Organisms: Vibrio cholerae
Confers Resistance To: nitrofurantoin
Validation Method: whole-genome sequencing and antimicrobial susceptibility testing
Source Database: Reslit

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