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Browse Mutations mecIP42L

GenemecI

repressor protein

Protein ChangeP42L

Nucleotide ChangeC125T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: oxacillin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Quantitation of mecA Transcription in Oxacillin-Resistant Staphylococcus aureus Clinical Isolates

PMID 12754244 · 2003

Mutations in mecI lead to decreased repression of mecA, resulting in increased oxacillin resistance.

Mutation Information

mecI: p.P42L / c.C125T

Protein Change: P42L
Nucleotide Change: C125T
Organisms: Staphylococcus aureus
Confers Resistance To: oxacillin
Validation Method: RT-PCR, Northern blot analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research