ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeT460A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: linezolid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea.

PMID 30027700 · 2018

Mutation in rplC was associated with linezolid resistance.

Mutation Information

rplC: p.T460A

Protein Change: T460A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: linezolid
Validation Method: sequencing and MIC determination
Source Database: Reslit

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