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Browse Mutations folP1V39I

Protein ChangeV39I

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: slightly reduced binding affinity
Resistance To: dapsone
Organisms: Mycobacterium leprae
Papers: 1

Paper Information1

1

A new Mycobacterium leprae dihydropteroate synthase variant (V39I) from Papua, Indonesia.

PMID 31016254 · 2019

Mutation Information

Protein Change: V39I
Organisms: Mycobacterium leprae
Confers Resistance To: dapsone
Effect on Function: slightly reduced binding affinity
Validation Method: molecular docking analysis and biochemical evaluation
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research