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ResLit

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Browse Mutations grlAE84L

GenegrlA

Protein ChangeE84L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Papers: 1

Paper Information1

1

In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.

PMID 36448795 · 2022

Mutation Information

Protein Change: E84L
Confers Resistance To: fluoroquinolones
Validation Method: selection of mutants with decreased susceptibility
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research