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Browse Mutations rplCG152V

GenerplC

Protein ChangeG152V

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased production of daptomycin
Resistance To: pleuromutilins
Organisms: Streptomyces roseosporus
Papers: 1

Paper Information1

1

Improvement of daptomycin production in Streptomyces roseosporus through the acquisition of pleuromutilin resistance.

PMID 24106707 · 2013

The mutation was associated with increased daptomycin production.

Mutation Information

Protein Change: G152V
Organisms: Streptomyces roseosporus
Confers Resistance To: pleuromutilins
Effect on Function: increased production of daptomycin
Validation Method: sequencing of rplC locus
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research