ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeR173G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: polymyxin b, polymyxins
Organisms: Acinetobacter baumannii
Papers: 1

Paper Information1

Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.

PMID 26779129 · 2015

Mutations in lpxD gene contribute to polymyxin resistance in AC30.

Mutation Information

lpxD: p.R173G

Protein Change: R173G
Organisms: Acinetobacter baumannii
Confers Resistance To: polymyxin bpolymyxins
Validation Method: Genome analysis; three amino acid mutations in lpxD of AC30
Source Database: Reslit

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