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Browse Mutations folAP21P

GenefolA

Protein ChangeP21P

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance
Resistance To: trimethoprim
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.

PMID 29871954 · 2018

Mutations in folA were identified as conferring resistance to trimethoprim.

Mutation Information

Protein Change: P21P
Organisms: Escherichia coli
Confers Resistance To: trimethoprim
Effect on Function: resistance
Validation Method: sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research