ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefabG1

ethionamide resistant fabG1

Protein ChangeG17V

Nucleotide ChangeGGT > GTC

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: isoniazid
Papers: 1

Paper Information1

Initial resistance to companion drugs should not be considered an exclusion criterion for the shorter multidrug-resistant tuberculosis treatment regimen.

PMID 32829049 · 2020

Mutations in fabG1 are associated with isoniazid resistance.

Mutation Information

fabG1: p.G17V / c.GGT > GTC

Protein Change: G17V
Nucleotide Change: GGT > GTC
Confers Resistance To: isoniazid
Validation Method: genotypic drug susceptibility testing (gDST) and phenotypic drug susceptibility testing (pDST)
Source Database: Reslit

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