ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneglpT

glycerol-3-phosphate/fosfomycin symporter

Protein ChangeE448K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fosfomycin
Organisms: Escherichia coli
Papers: 2

Paper Information2

Genomic Analysis of Antibiotic Resistance and Virulence Profiles in Escherichia coli Linked to Sternal Bursitis in Chickens: A One Health Perspective.

PMID 40711335 · 2025

Mutation Information

glpT: p.E448K

Protein Change: E448K
Organisms: Escherichia coli
Confers Resistance To: fosfomycin
Validation Method: Whole genome sequencing
Source Database: Reslit

Characterization of Fosfomycin and Nitrofurantoin Resistance Mechanisms in Escherichia coli Isolated in Clinical Urine Samples.

PMID 32847131 · 2020

Multiple substitutions detected in both resistant and susceptible isolates

Mutation Information

glpT: p.E448K

Protein Change: E448K
Organisms: Escherichia coli
Confers Resistance To: fosfomycin
Validation Method: PROVEAN analysis
Source Database: Reslit

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